Business Number: 832018279RR0001

Our mission is to Accelerate the Cure for Type 1 Diabetes by directly funding cure-based diabetes researcher Dr. James Shapiro and his team at the University of Alberta.

The Diabetes Research Institute Foundation Canada (DRIFCan) was established in 2005 to fundraise for diabetes research, specifically for the Edmonton Protocol. The Edmonton Protocol is a method of implantation of pancreatic islets for the treatment of type 1 diabetes mellitus, specifically "brittle" type 1 diabetics prone to hypoglycemic unawareness. The protocol is named for the islet transplantation group at the University of Alberta in the Canadian city of Edmonton, where the protocol was first devised in the late 1990s, and published in The New England Journal of Medicine in July 2000. Dr. James Shapiro is the Director of the Clinical Islet Cell Transplant Program at the University of Alberta, where there are several ongoing human clinical trials in islet transplantation:

1. Treatment regimes to improve islet cell mass and function (BMX)

2. Improve single donor success rate (Aralast NP)

3. Alternate sites for islet transplantation (Gastric sub-mucosal space, and now we are excited to be in collaboration with Miami for the BioHub platform/trials).

4. We have stem cell human trials (in collaboration with ViaCyte) to treat chronic T1DM subjects and an Immunologic Reset clinical trial for new onset T1DM.

Dr. Shapiro also has an active research + development lab in the Alberta Diabetes Institute, currently the "Deviceless' technology is at pre-clinical development stage, with plans to move forward with a pilot clinical trial soon.

Our Clinical Islet Transplant Program has performed more than 500 transplants to date, more than any other islet transplant centre in the world. The program is funded by grants (NIH, JDRF, AIHS), by the Alberta government and also through donations.

As well, there are active human trials using stem cell transplants.

There are over 450 million people around the world with a form of diabetes, out of that 10% have Type 1, out of that over 300,000 live in Canada.  We must support Dr. Shapiro and his team, so they CAN cure Type 1 so they WILL cure Type 1!

Thank you for your support!

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