Since its incorporation in 1972, the Quesnel Tillicum Society has worked continuously in its mission to improve the quality of life and meet the needs of First Nations and other peoples faced with adjusting to the social, economic and cultural lifestyles of the Community. The present Friendship Centre was built in 1974. With the long term goal of making a true difference economically, environmentally and socially through service to the community, guided by accountability and a strong code of ethics grounded in First Nations Principals, the Quesnel Tillicum Society has helped individuals and families surmount problems and achieve success for over 40 years in the Urban environment.

Serving the City of Quesnel and Area, The Quesnel, BC Tillicum Society / Native Friendship Centre offers FAS info, drug & alcohol programs, employment information and counseling, youth outreach, and family support. In addition to providing Hall rental facilities for community events, The Quesnel Tillicum Society currently hosts an annual Pow Wow and an Aboriginal Day Celebration.

Current programs being offered at the Friendship Centre include Fetal Alcohol & Drug Effects Worker, Mom's Group, Mom's for Recovery Program, Drug and Alcohol Program, Youth Employment Counselor, Youth Outreach,  Family Support Worker, Family & Legal Law Advocates,  Family Finder & Cultural Programming.

The Quesnel Tillicum Society is now fundraising to build affordable housing.